[HTML][HTML] A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

D Li, X Chang, JJ Connolly, L Tian, Y Liu, EJ Bhoj… - Scientific reports, 2017 - nature.com
… genetic risk factor that approached genome-wide significance … = 0.04), suggesting a
variant-mediated dysregulation of leptin … variant support the nominal association. This …

Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links

C de Jorge Martínez, G Rukh, MJ Williams… - Journal of Genetics and …, 2022 - Elsevier
… the study was well-powered, suggesting that they may not be involved in aetiology of AN. …
may predispose to BMI dysregulation in interaction with other genetic or environmental factors. …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

…, Anorexia Nervosa Genetics Initiative… - Nature …, 2019 - nature.com
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric
origins for anorexia nervosa | … Genome-wide association study identifies eight risk loci and …

[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations

L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
… 2 of anorexia nervosa was 0.20 (SE=0.02), suggesting that a … GWAS loci for complex
disorders, the region implicated is … dysregulation of appetite and weight in anorexia nervosa. …

[HTML][HTML] Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia …

L Bang, S Bahrami, G Hindley, OB Smeland… - Translational …, 2023 - nature.com
… statistics from relevant genome-wide association studies (GWAS… Our findings suggest a large
degree of genetic overlap … associations with genes involved in metabolic dysregulation [21]…

A genome-wide association study of anorexia nervosa

V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - nature.com
… No findings reached genome-wide significance. Two intronic variants were suggestively …
chance (P=4 × 10 −6 ), strongly suggesting that true findings exist but our sample, the largest yet …

Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

…, Eating Disorders Working Group of the … - American journal of …, 2017 - Am Psychiatric Assoc
… modest odds ratio of 1.2 and implicates a broad region encompassing … Our results, in contrast,
suggest that genetic factors may … dysregulation of appetite and weight in anorexia nervosa. …

A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - cdr.lib.unc.edu
Anorexia nervosa (AN) is a complex and heritable eating … candidate gene studies nor an
initial genome wide association study (… of weight dysregulation to AN, genes implicated in the …

[HTML][HTML] Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa

LM Huckins, K Hatzikotoulas, L Southam… - Molecular …, 2018 - nature.com
… -chip based genome-wide association studies (GWAS) in … in AN, suggesting shared
biological dysregulation between the two … We obtained a list of 340 genes involved in modifying …

Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder

…, Eating Disorders Working Group of the Psychiatric … - Molecular …, 2020 - nature.com
… of shared risk between AN and OCD and suggest that larger … Larger samples, however,
are needed to conclusively implicate … Meta-analysis of genome-wide association studies for …